Biological Mechanisms of Aging & Application in Clinical Research
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This course provides a comprehensive overview of the biological processes and mechanisms that contribute to aging and age-related disease, emphasizing their relevance to geroscience and clinical research. It examines how advances in the understanding of aging biology can inform the development and evaluation of geroscience interventions, the use of preclinical models, and the design and translation of research into clinical applications. The course also introduces approaches for assessing biological aging and evaluating biomarkers and outcomes in geroscience research.
Topics include:
- Introduction and Societal Implications
- Physiology of Human Aging
- Preclinical Aging Models
- Energy and Metabolism
- Cellular Senescence
- Damage and Repair
- Epigenetics, Stem Cells, and Regeneration
- Geroscience Interventions
- Design of Clinical Trials in Geroscience
- Geroscience Biomarkers - Discovery and Validation
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Privacy Acknowledgment & Pre-Course Questions
Privacy Acknowledgment & Pre-Course Questions
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Explore the scientific foundations, societal impact, and ethics of geroscience and precision gerontology. This course examines human longevity trends, public health significance, and the economic value of aging research while addressing responsible communication, ethical challenges, and intersectionality within the geroscience enterprise.
Gain a comprehensive introduction to geroscience and the physiology of human aging in this course on translational geroscience and precision gerontology. Explore historical and current trends in human longevity, the limits of life expectancy, and geroscience’s growing role as a public health priority. Learn to evaluate aging research responsibly, avoid exaggeration in scientific communication, and understand the health and economic value of geroscience. The course also examines ethical, social, and political considerations shaping the field, including public health frameworks, epistemic uncertainty in aging research, and the importance of equity and intersectionality in advancing the geroscience enterprise. Designed for learners interested in aging science, public health, and policy, this course provides essential foundations for understanding how geroscience can improve health across the lifespan and inform evidence-based decision-making.
Lecture 1: Scientific Foundations of Translational Geroscience and Precision Gerontology
By the end of this lecture, learners will be able to:
- Understand the historical view of human longevity
- Learn about recent trends in life expectancy and why it’s limited
- Discover that Geroscience has become a critically important public health initiative
Lecture 2: Scientific Foundations of Translational Geroscience and Precision Gerontology
By the end of this lecture, learners will be able to:
- Explain how to avoid embellishment and exaggeration in aging science
- Describe the rationale supporting Geroscience
- Interpret the health and economic value of Geroscience
Lecture 3: Ethics and the Geroscience Enterprise
By the end of this lecture, learners will be able to:
- Identify some of the ethical, social, and political challenges facing geroscience
- Define public health (…to help situate geroscience in the biomedical scientific enterprise)
- Explain the ethical significance of “epistemic uncertainty” for research on, and communication about, the biology of aging
- Comprehend situating egalitarian advocacy within the geroscience enterprise (introduction to the concept of “intersectionality”)
Lecture 4: Ethics and the Geroscience Enterprise
By the end of this lecture, learners will be able to:
- Identify some of the ethical, social and political challenges facing geroscience
- Scientific enterprise)
- Explain the ethical significance of “epistemic uncertainty” for research on, and communication about, the biology of aging
- Situating egalitarian advocacy within the geroscience enterprise (introduction to the concept of “intersectionality”)
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Module 1: (Title)
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Module 2: (Title)
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Preclinical Aging Models introduces core principles for selecting and using animal models in aging research. The course examines major preclinical models, their biological strengths and limitations, and emphasizes rigorous, reproducible study design to improve translation, including outcome measure selection and links among mechanisms, biomarkers, and outcomes.
Preclinical Aging Models introduces researchers to the principles and practices that guide the effective use of animal models in aging and geroscience research. The course begins with the logic of animal model selection, examining key tradeoffs among species, available genotypic configurations, and the scientific importance of including both sexes in preclinical studies. Learners then explore the biology of major animal models used in aging research, comparing species-specific characteristics relevant to geroscience. The strengths and limitations of commonly used models—including C. elegans, fruit flies, and laboratory rodents—are evaluated to help researchers align model choice with research questions. The course concludes with a focus on study design strategies that enhance the translation of preclinical findings to human aging and therapeutics. Core concepts such as rigor, repeatability, replicability, reproducibility, and translatability are integrated throughout. Participants will also examine outcome measure selection across species, internal and external validity, and the relationships among mechanisms, biomarkers, and outcomes. Together, these modules provide a cohesive framework for designing robust, interpretable, and translationally relevant preclinical aging studies.
Lecture 1: Logic of Animal Model Selection
By the end of this lecture, learners will be able to:
- Define the logic of animal model selection
- Identify a basic tradeoff in animal model species selection
- Describe the various genotypic configurations available for research species
- Understand the rationale for employing both sexes
Lecture 2: Biology of Major Animal Models used in Aging Research
By the end of this lecture, learners will be able to:
- Identify the main animal models used in aging research
- Compare basic information relevant to geroscience studies about the biology of these species
- Describe strengths and weaknesses of C. elegans as a model
- Describe the strengths and weaknesses of the fruit fly as models
- Describe the strengths and weaknesses of laboratory rodents as models
Lecture 3: Study Design to Optimize Translation of New Therapeutics
By the end of this lecture, learners will be able to:
- Understand the concepts of repeatability, replicability, reproducibility, rigor and translatability
- Evaluate the choice of outcome measures as criteria for efficacy across species
- Understand the concepts of internal and external validity, reductionism and generalizability
- Understand the relationship between mechanism, biomarker and outcome measure in translational study design
Steven N. Austad, PhD
American Federation for Aging Research
Dr. Austad is a Distinguished Professor and Protective Life Endowed Chair in Healthy Aging Research of the Department of Biology, University of Alabama at Birmingham and Scientific Director of the American Federation for Aging Research. In addition, he directs the NIH-supported UAB Nathan Shock Center of Excellence in the Basic Biology of Aging, one of only six such Centers in the United States. He is also the Co-director of the Nathan Shock Centers Coordinating Center and serves on the Executive Committee of the National Institute on Aging’s Research Centers Collaborative Network.
Dr. Austad’s current research seeks to understand the underlying causes of aging with a long-term goal of developing medical interventions that slow the age-related decay in human health. Dr. Austad is the author of more than 200 scientific peer-reviewed publications covering nearly every aspect of aging from cells to societies. Dr. Austad is a fellow of the American Association for the Advancement of Science, and of the Gerontological Society of America. He has received multiple prestigious awards for his research work.Caroline Zeiss, DVM, PhD
Chief of Pathology, Department of Comparative Medicine
Yale School of Medicine
Caroline Zeiss, DVM, PhD, is a dual-boarded laboratory animal veterinarian and veterinary pathologist with doctoral training in the translational use of large animal models. She earned her veterinary degree from Onderstepoort, University of Pretoria, South Africa, and completed a small animal medicine and surgery internship at the University of Pennsylvania. Dr. Zeiss completed her pathology residency and PhD at the Cornell University College of Veterinary Medicine, followed by a faculty appointment at Yale University.
She currently serves as Chief of Pathology in the Department of Comparative Medicine. Her independent and collaborative research focuses on the development of translational animal models in infectious disease and neuroscience. Although trained as a general anatomic pathologist, her expertise is concentrated in ophthalmic and neuropathology, including long-standing collaborations evaluating the toxicity and efficacy of gene therapies and other neurologic interventions. More recently, her work has expanded to modeling influenza and SARS-CoV-2 co-infection and coronavirus propagation in rodents. Her clinical practice centers on nonhuman primate care, with emphasis on anesthesia, pain management, imaging, and internal medicine in aging macaques.
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This module introduces the foundations of metabolism and metabolic flux in the study of aging. Learners begin by examining how mice and rats differ in aging and metabolism. The course also considers how animal strain and sex can shape research outcomes. A second lecture explains how the body stores and mobilizes glucose and fat. Learners explore the cellular pathways that capture energy from these molecules. The course also introduces mTORC1 and AMPK, two key sensors that regulate cellular energy use. A final lecture explains metabolic flux, why dynamic measurements can be more informative than snapshots, and one approach for measuring flux. Learners conclude by examining protein turnover and how it may be targeted to support healthier aging.
This module introduces the foundations of metabolism and metabolic flux in the study of aging. Learners begin by examining how mice and rats differ in aging and metabolism. The course also considers how animal strain and sex can shape research outcomes. A second lecture explains how the body stores and mobilizes glucose and fat. Learners explore the cellular pathways that capture energy from these molecules. The course also introduces mTORC1 and AMPK, two key sensors that regulate cellular energy use. A final lecture explains metabolic flux, why dynamic measurements can be more informative than snapshots, and one approach for measuring flux. Learners conclude by examining protein turnover and how it may be targeted to support healthier aging.
Lecture 1: Preclinical Models and Methods for Studying Metabolic Flux
By the end of this lecture, learners will be able to:
- Understand how mice and rats differ regarding aging and metabolism
- Understand how strain impacts outcomes of aging and metabolism
- Understand how sex interacts with species and strain
Lecture 2: Core Energy Metabolism and Signaling
By the end of this lecture, learners will be able to:
- Understand storage and mobilization of glucose and fat (lipids)
- Learn cellular pathways to take up and harvest energy from these molecules
- Become familiar with two key intracellular energy sensors, mTORC1 and AMPK
Lecture 3: Metabolic Flux and Protein Metabolism
By the end of this lecture, learners will be able to:
- Understand the concept of metabolic flux
- Understand the limitations of snapshots compared to moving pictures
- Describe one approach for measuring flux
- Understand important factors in the flux (turnover) of protein
- Understand how to target protein turnover to slow aging
Joseph A. Baur, PhD
Professor, Department of Physiology, Institute for Diabetes, Obesity, and Metabolism
Director, Rodent Metabolic Phenotyping Core, Perelman School of Medicine, University of Pennsylvania
Joseph A. Baur, PhD, is a Professor in the Department of Physiology and the Institute for Diabetes, Obesity, and Metabolism, as well as Director of the Rodent Metabolic Phenotyping Core at the Perelman School of Medicine, University of Pennsylvania. His long-term interest is in the basic mechanisms that lead to aging, which is a critical risk factor for the major causes of morbidity and mortality in the western world, including cardiovascular disease, diabetes, cancer, and neurodegenerative disorders. After completing his undergraduate degree in Canada, he travelled to UT Southwestern in Dallas, Texas, to pursue his PhD studies on human telomere biology. For his postdoctoral studies, he moved to Harvard Medical School to study sirtuin enzymes, which use NAD+ to alter post-translational modifications and have been hypothesized to play a role in aging. The Baur lab is currently focused on the use of small molecules to understand and mimic the health-promoting effects of dietary manipulations in rodents, with a particular focus on nicotinamide adenine dinucleotide (NAD+) metabolism.
Benjamin Miller, PhD
G.T. Blankenship Chair in Aging Research and Department Chair of the Aging and Metabolism Research Program
Oklahoma Medical Research Foundation (OMRF)
Dr. Miller received a PhD from UC-Berkeley and completed a post-doc at the Muscle Research Center in Copenhagen, Denmark. He is currently G.T. Blankenship Chair in Aging Research and Department Chair of the Aging and Metabolism Research Program at the Oklahoma Medical Research Foundation (OMRF). Dr. Miller’s expertise is in skeletal muscle, aging, mitochondria, stable isotope labeling, proteostasis, and drug and lifestyle (primarily exercise) interventions. His work with tracers and in muscle aging is nationally recognized and has led to many collaborations, extensive mentoring, and leadership positions. Dr. Miller’s work is almost exclusively focused on prolonging the period spent in good health (i.e., healthspan) by targeting mitochondrial energetics and proteostatic maintenance. The Miller lab is truly translational, with studies spanning pre-clinical models, clinical trials, and back. The Miller lab has focused on training the next generation of scientists, and many from the lab have gone on to their own exceptional careers
The Supplemental Materials PDFs include additional resources, references, and information to support and enhance your learning.
- Cases/Discussion Questions
- Glossary of Terms
- References
Lecture 1: Preclinical Models and Methods for Studying Metabolic Flux
Download Lecture 1 Slides (PPT)
Download Lecture 1 Slides (PDF)
Download Lecture 1 Supplemental Materials
Lecture 2: Core Energy Metabolism and Signaling
Download Lecture 2 Slides (PPT)
Download Lecture 2 Slides (PDF)
Download Lecture 2 Supplemental Materials
Lecture 3: Metabolic Flux and Protein Metabolism
Download Lecture 3 Slides (PPT)
Download Lecture 3 Slides (PDF)
Download Lecture 3 Supplemental Materials
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This module introduces cellular senescence as a key hallmark of aging and examines its complex roles in health and disease. Learners will explore how cellular senescence is defined and how it differs in laboratory models and living organisms. The module reviews the major mediators and mechanisms that drive cells into senescence. It also examines preclinical models used to study senescence and highlights the beneficial functions senescent cells can serve. Building on this foundation, learners will consider how senescent cell burden is measured in preclinical models and humans. The module addresses the diversity of senescent cells and how their characteristics can vary across tissues and conditions. Learners will assess evidence linking senescent cells to age-related diseases. The module concludes with an overview of emerging therapeutic strategies designed to target senescent cells and support healthier aging.
This module introduces cellular senescence as a key hallmark of aging and examines its complex roles in health and disease. Learners will explore how cellular senescence is defined and how it differs in laboratory models and living organisms. The module reviews the major mediators and mechanisms that drive cells into senescence. It also examines preclinical models used to study senescence and highlights the beneficial functions senescent cells can serve. Building on this foundation, learners will consider how senescent cell burden is measured in preclinical models and humans. The module addresses the diversity of senescent cells and how their characteristics can vary across tissues and conditions. Learners will assess evidence linking senescent cells to age-related diseases. The module concludes with an overview of emerging therapeutic strategies designed to target senescent cells and support healthier aging.
Lecture 1: Introduction to Cell Senescence
By the end of this lecture, learners will be able to:
- Define cellular senescence
- Differentiate between cellular senescence in vitro vs in vivo
- Summarize mediators and mechanisms of senescence
- Describe preclinical models of senescence
- Acknowledge beneficial roles of senescent cells
Lecture 2: Cellular Senescence in Disease
By the end of this lecture, learners will be able to:
- Understand senescent cell burden in preclinical models and humans
- Describe the heterogeneity of senescent cells
- Discuss the contribution of senescent cells to age-related disease
- List several therapeutic strategies in development to target senescent cells
Nabora Reyes de Barboza
Assistant Professor of Cell and Developmental Biology
University of California San Diego
Dr. Nabora Reyes de Barboza is an Assistant Professor of Cell and Developmental Biology at UC San Diego who studies how senescent cells regulate tissue formation, homeostasis, and regeneration, with a primary focus on the lung. She earned her BS in Biochemistry and Molecular Biology and MS in Quantitative and Systems Biology from UC Merced, where she investigated Nox proteins in hepatitis C signaling. She completed her PhD at UC Irvine under Dr. Ken Cho, studying BMP signaling in early embryonic development. As a postdoctoral fellow at UCSF with Dr. Tien Peng, Dr. Reyes explored senescent cell signaling during lung regeneration, developing a novel p16INK4a reporter mouse model that revealed a supportive role for senescent fibroblasts in tissue repair. Her independent research program focuses on the context-dependent roles of senescent fibroblasts across distinct lung microenvironments, particularly in aging and injury. Her lab investigates fibroblast-immune interactions, responses to viral infection, aging-associated changes, and the secreted factors that drive repair. Dr. Reyes’s work integrates developmental biology, regenerative medicine, and aging research to uncover new therapeutic strategies for respiratory disease. She is the recipient of several prestigious awards, including the NRSA F32, UC Chancellor’s and UCSF-CIRM Postdoctoral Fellowships, and the NHLBI K99/R00 Pathway to Independence Award.Allyson Palmer, MD, PhD
Consultant, Division of Hospital Internal Medicine, Department of Internal Medicine
Mayo Clinic
Allyson Palmer, MD, PhD, is a board-certified internist with expertise in the care of older adults. She is also an Assistant Professor of Medicine at Mayo Clinic Alix School of Medicine. Dr. Palmer attended medical school at the Mayo Clinic Alix School of Medicine. She trained in Internal Medicine and completed subspecialty training in Geriatric Medicine at Mayo Clinic. Dr. Palmer's clinical practice focuses on acute care for older adults admitted to the hospital, as well as consultative and perioperative care for hospitalized older adults. Her research interests include cellular senescence, metabolic dysfunction of aging and obesity, and delirium.
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Explore key biological mechanisms of aging, including autophagy, proteostasis, oxidative stress, and inflammaging. Learn how cellular damage, protein homeostasis, inflammation, and stress responses influence aging processes and age-related diseases, and how these pathways support research on healthy aging and longevity.
This module series explores the core biological mechanisms that drive aging and age-related disease. Topics include autophagy, the cellular recycling process essential for maintaining homeostasis, and how its decline contributes to cellular dysfunction with age. Learners will also examine proteostasis and macromolecular damage, including how cells maintain protein health and how disruptions are linked to disease. The modules review oxidative stress and the free radical theory of aging, along with key molecular pathways, antioxidant responses, and stress-response mechanisms. In addition, the concept of inflammaging is introduced, highlighting the differences between acute and chronic inflammation, the molecular pathways involved, and the relationship between chronic inflammation and immunosenescence. Together, these topics provide a foundational understanding of the biological processes that influence aging, longevity, and the development of age-related conditions.
Lecture 1: Autophagy
By the end of this lecture, learners will be able to:
- Define autophagy, a cellular recycling process critical for maintaining cellular homeostasis
- Discuss molecular links between autophagy and aging, including how autophagy declines with age, leading to cellular dysfunction
- Summarize paradigms that can boost autophagy and promote healthy aging
- Explain limitations in assays used to monitor autophagy, including in humans
Lecture 2: Proteostasis & Macromolecular Damage
By the end of this lecture, learners will be able to:
- Introduce concept of macromolecular damage to proteins, which can happen during aging
- Define the proteostasis (protein homeostasis) network, a set of molecular mechanisms the cell uses to maintain protein homeostasis, including repair and degradation
- Summarize diseases linked to proteostasis
Lecture 3: Oxidative Stress
By the end of this lecture, learners will be able to:
- Define oxidative stress
- Discuss the free radical theory of aging that provides a foundation for the research performed today
- Identify molecular pathways that lead to oxidative stress
- Discuss antioxidants and stress response mechanisms
Lecture 4: Inflammaging
By the end of this lecture, learners will be able to:
- Discuss acute versus chronic inflammation
- Define inflammaging and the research that led to the concept
- Identify the cell types and molecular pathways that underlie inflammaging
- Discuss how inflammaging is linked with immunosenescence
Malene Hansen, PhD
Professor & Chief Scientific Officer
Buck Institute
Malene Hansen, PhD is a Professor and Chief Scientific Officer at the Buck Institute for Research on Aging. She is a leading researcher in the biology of aging, with a background in studying the molecular mechanisms of aging using nematode models and cell culture systems. Dr. Hansen’s laboratory focuses on understanding how the cellular recycling process known as autophagy is linked to aging and longevity. Her work aims to uncover the biological mechanisms that drive aging and to identify pathways that may support healthier aging and improved lifespan.
Christina D. Camell
Assistant Professor
University of Minnesota
Christina D. Camell, PhD is an Assistant Professor in the Department of University of Minnesota Department of Biochemistry, Molecular Biology and Biophysics. Her research focuses on the biological mechanisms that link inflammation, metabolism, and aging. Dr. Camell’s work examines how immune cells function in non-lymphoid organs during aging and in the context of metabolic disease. Through her research, she aims to better understand how age-related changes in the immune system contribute to chronic disease and to identify new strategies to improve health and resilience in aging populations.
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Learn key concepts in stem cell aging, cellular reprogramming, and epigenetics. Explore how stem cell function changes with age, the potential of reprogramming and rejuvenation strategies, and how epigenetic changes are linked to aging and cancer.
This module explores the role of stem cells and epigenetics in the biology of aging. Learners will examine the defining features of stem cells, how somatic stem cell function declines with age, and examples of age-related stem cell dysfunction. The content also introduces cellular reprogramming, including partial reprogramming and direct reprogramming, and reviews their potential clinical applications as well as current challenges in the aging field. In addition, the modules explore epigenetic regulation, common assays used to study epigenetic changes, and how epigenetic alterations are linked to aging, stem cell function, and cancer. Together, these topics provide a foundation for understanding how regenerative biology and epigenetics contribute to aging research and the development of future therapies.
Lecture 1: Stem Cells
By the end of this lecture, learners will be able to:
- Define stem cells
- Understand the features of somatic stem cells
- Give examples of impaired stem cell function with age
- Describe interventions that improve stem cell function
Lecture 2: Reprogramming and Rejuvenation
By the end of this lecture, learners will be able to:
- Understand cellular reprogramming
- Define partial reprogramming
- Understand the clinical potential of partial reprogramming and its challenges
- Describe direct reprogramming and its uses in the aging field
Lecture 3: Epigenetic Association with Cancer
By the end of this lecture, learners will be able to:
- Define epigenetic regulation and assays used to study them
- Convey connections between epigenetics and aging
- Describe reported alterations associated with aging in adult stem cells
- Summarize epigenetic association with cancer
Ashley Webb, PhD
Associate Professor
The Buck Institute for Research on Aging
Ashley Webb, PhD is an Associate Professor at the Buck Institute for Research on Aging. Her research focuses on the biological mechanisms of aging, with particular expertise in stem cell aging and brain aging. Dr. Webb’s work aims to better understand how aging affects stem cell function and the brain, with the goal of identifying strategies that support healthy aging and improve resilience to age-related decline.
Isabel Beerman, PhD
Stadtman Tenure Track Investigator
National Institute on Aging
Isabel Beerman, PhD is a Stadtman Tenure-Track Investigator at the National Institute on Aging. Her research focuses on hematopoietic stem cell aging and the epigenetic alterations that drive age-related changes in stem cell function. Dr. Beerman’s work aims to better understand how aging affects stem cells at the molecular level and to identify mechanisms that may support healthier aging and improved regenerative capacity.
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Lecture 1: (Coming Soon)
By the end of this lecture, learners will be able to:
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Lecture 2: Age Later: Gerotherapeutics
By the end of this lecture, learners will be able to:
- Connect a drug to geroscience (hence-Gerotherapuetics)
- Identify current evidence-based opportunities
- Select an intervention for a clinical context
- Foresee a way for FDA approval of Gerotherapeutics
Nir Barzilai, MD
Professor
Albert Einstein College of Medicine
Dr. Nir Barzilai is the director of the Institute for Aging Research at the Albert Einstein College of Medicine and the Director of the Paul F. Glenn Center for the Biology of Human Aging Research and of the National Institutes of Health’s (NIH) Nathan Shock Centers of Excellence in the Basic Biology of Aging. He is the Ingeborg and Ira Leon Rennert Chair of Aging Research, professor in the Departments of Medicine and Genetics, and member of the Diabetes Research Center and of the Divisions of Endocrinology & Diabetes and Geriatrics.
Dr. Barzilai’s research interests are in the biology and genetics of aging. One focuses on the genetic of exceptional longevity, where we hypothesize and demonstrated that centenarians have protective genes, which allows the delay of aging or for the protection against age-related diseases. In a Program he is leading we take full advantage of phenotypes, DNA, and cells from the Ashkenazi Jewish families with exceptional longevity and the appropriate controls and his group have established at Einstein (over 2600 samples of which ~670 are centenarians) and discovered underling genomic differences associated with longevity. Longevity Genes Project (LGP) is a cross-sectional, on-going collection of blood and phenotype from families with centenarian proband. LonGenity is a longitudinal study of 1400 subjects, half offspring of parents with exceptional longevity, validating and following their aging in relationship to their genome. The second direction, for which Dr. Barzilai is holding an NIH Merit award that focuses on the metabolic decline of aging, and his team hypothesize that the brain leads this decline. His lab has identified several central pathways that specifically alter body fat distribution and insulin action and secretion by intraventricular or hypothalamic administration of several peptides that are modulated by aging including: Leptin, IGF-1, IGFBP3 and resveratrol.
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Module 1: (coming soon)
By the end of this module, learners will be able to:
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Module 2: Clinical Trials in Geroscience
By the end of this module, learners will be able to:
- Identify the phases of clinical trials
- Review two examples
- Review why evidence coming from randomized clinical trials is considered the most rigorous
Stephen B. Kritchevsky, PhD
Professor
Wake Forest University School of Medicine
Stephen Kritchevsky is the Toby R. Alligood, MD EndowedProfessor in Geroscience at Wake Forest University School ofMedicine. There he directs the Claude D. Pepper Older AmericansIndependence Center & the Sticht Center for Healthy Aging andAlzheimer’s Prevention. He is a Principal Investigator of theTranslational Geroscience Network, and is involved in designingand leading clinical trials of geroscience-inspired interventionsincluding senolytics, metformin and caloric restriction.
Resources for Educators
Each lecture includes a set of downloadable resources designed to support geroscience instruction in a range of educational settings. Materials include PowerPoint slides, presentation PDFs, and supplemental teaching resources such as case studies, discussion questions, a glossary of key terms, and references. You may also stream or download the recorded lecture, which combines the presentation slides with the speaker’s video and audio, for your own preparation or for use with learners.
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